Specificity
This antibody shows specificity to E.coli O157 in a simple ELISA. Escherichia coliare Gram negative bacterium that are commonly found in the lower intestine of warm-blooded organisms (endotherms). Their serological types are determined in combination with somatic antigens (O group: O1-O173) and flagella antigens (H type: H1-H56). TheE. colithat cause intestinal infectious diseases including diarrhea, acute gastritis or colitis are referred to as pathogenicE. coli, which are classified into the following 4 groups according to differences in the mode of pathogenicity; enteropathogenicE. coli(EPEC), enteroinvasiveE. coli(EIEC), enterotoxigenicE. coli(ETEC) and enterohemorrhagicE. coli(EHEC). Although the identification of pathogenicE. colirequires verification of their pathogenicity, pathogenicE. colioften have specific serotypes; therefore, typing of the serogroup and serotype is necessary in screening pathogenicE. coli.