Anti-DPP4 Antibody [M-A261] (PE) (A281006)

Anti-DPP4 Antibody [M-A261] (PE)

Mouse monoclonal [M-A261] antibody to DPP4 (PE).

This antibody recognises human dipeptidyl peptidase 4, also known as adenosine deaminase complexing protein 2, CD26, TP103, ADABP or DPP IV. CD26 is a 766 amino acid ~110 kDa single pass type II transmembrane glycoprotein expressed by activated T cells, B cells and macrophages. A soluble form of CD26 can be derived by cleavage of the membrane bound form between residues 38-39 (Uniprot: 27487).CD26 acts as a functional receptor for the pathogenic Middle East respiratory syndrome coronavirus [MERS-CoV] , a severe and frequently fatal disease in humans and marmosets sharing identical CD26 sequence at the site of interaction with the MERS-CoV spike protein (Lu et al. 2013, Wang et al. 2013). Mouse anti Human CD26 antibody, clone M-A261 has been used successfully for the immunohistochemical detection of CD26 on formalin fixed, paraffin embedded tissues and the demonstration of elevated CD26 expression in thyroid neoplasia (Kholová et al. 2003). Mouse anti Human CD26 antibody, clone M-A261 has also been used for the immunohistochemical detection of CD26 on cryostat sections using both immunoperoxidase and immunofluorescence staining in liver biopsies from NASH patients.

Flow Cytometry: Neat, Use 10µl of the suggested working dilution to label 10⁶ cells or 100µl whole blood

Human

Human T-cell leukemia cells (T-CLL).

Mouse

Monoclonal

M-A261

IgG1

PE

Excitation: 565nm, Emission: 578nm

Reconstitution dependent.

Lyophilized

Reconstitute with 1 ml of distilled water

Supplied in Phosphate Buffered Saline with 1% BSA, 5% Sucrose, and 0.09% Sodium Azide.

Lyophilized: Store at 4°C. Reconstituted: Store undiluted at 4°C. Do not freeze! This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.

Mouse anti Human CD26 antibody, clone M-A261, recognizes human dipeptidyl peptidase 4, also known as adenosine deaminase complexing protein 2, CD26, TP103, ADABP or DPP IV. CD26 is a 766 amino acid ~110 kDa single pass type II transmembrane glycoprotein expressed by activated T cells, B cells and macrophages. A soluble form of CD26 can be derived by cleavage of the membrane bound form between residues 38-39 (Uniprot: 27487).CD26 acts as a functional receptor for the pathogenic Middle East respiratory syndrome coronavirus [MERS-CoV] (Raj et al. 2014), a severe and frequently fatal disease in humans and marmosets sharing identical CD26 sequence at the site of interaction with the MERS-CoV spike protein (Lu et al. 2013, Wang et al. 2013).Mouse anti Human CD26 antibody, clone M-A261 has been used successfully for the immunohistochemical detection of CD26 on formalin fixed, paraffin embedded tissues and the demonstration of elevated CD26 expression in thyroid neoplasia (Kholová et al. 2003). Mouse anti Human CD26 antibody, clone M-A261 has also been used for the immunohistochemical detection of CD26 on cryostat sections using both immunoperoxidase and immunofluorescence staining in liver biopsies from NASH patients (Balaban et al. 2007).

ADA-binding protein, ADABP, ADCP 2, ADCP-2, ADCP2, Adenosine deaminase complexing protein 2, CD 26, CD26, CD26 antigen, CD26 antigen 3, Dipeptidyl peptidase 4, Dipeptidyl peptidase 4 soluble form, Dipeptidyl peptidase IV, Dipeptidyl peptidase IV membrane form, Dipeptidyl peptidase IV soluble form, Dipeptidyl peptidase, intestinal, Dipeptidylpeptidase 4, Dipeptidylpeptidase IV, Dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2), DPP 4, DPP IV, DPP IV estoenzyme, DPP4_HUMAN, DPPIV, Intestinal dipeptidyl peptidase, T cell activation antigen CD26, T-cell activation antigen CD26, TP 103, TP103

This product is for research use only. It is not intended for diagnostic or therapeutic use.