Anti-DPP4 Antibody [DPP4/7415] (A314895)

Anti-DPP4 Antibody [DPP4/7415]

Mouse monoclonal [DPP4/7415] antibody to DPP4.

Recognizes a glycoprotein of 110kDa, identified as CD26 (Workshop VI; Code: N-L039). It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti-CD3-induced IL-2 production. In Western blotting, this MAb reacts with only glycosylated CD26, but not with the deglycosylated form. It does not prevent ADA binding to CD26.

WB, IHC-P

Human lymph nodes or tonsil.

WB: 1-2 µg/ml, IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 1-200) of human DPP4 protein. The exact sequence is proprietary.

Mouse

Monoclonal

DPP4/7415

kappa

Unconjugated

Protein A/G chromatography.

200 µg/ml

110 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

ADA-binding protein, ADABP, ADCP 2, ADCP-2, ADCP2, Adenosine deaminase complexing protein 2, CD 26, CD26, CD26 antigen, CD26 antigen 3, Dipeptidyl peptidase 4, Dipeptidyl peptidase 4 soluble form, Dipeptidyl peptidase IV, Dipeptidyl peptidase IV membrane form, Dipeptidyl peptidase IV soluble form, Dipeptidyl peptidase, intestinal, Dipeptidylpeptidase 4, Dipeptidylpeptidase IV, Dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2), DPP 4, DPP IV, DPP IV estoenzyme, DPP4_HUMAN, DPPIV, Intestinal dipeptidyl peptidase, T cell activation antigen CD26, T-cell activation antigen CD26, TP 103, TP103