Anti-Dopamine beta Hydroxylase Antibody [DBH/7222] - BSA and Azide free (A316277)

$765

Mouse monoclonal [DBH/7222] antibody to Dopamine beta Hydroxylase for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-Dopamine beta Hydroxylase Antibody [DBH/7222] - BSA and Azide free
Description
Mouse monoclonal [DBH/7222] antibody to Dopamine beta Hydroxylase.
Specificity
Dopamine -hydroxylase (DBH) catalyzes the conversion of dopamine to noradrenaline in the biosynthesis of catecholamines. DBH is selectively expressed in noradrenergic and adrenergic neurons, as well as in neuroendocrine cells, and it serves as a specific protein marker for noradrenergic processes. The active form of DBH is a homotetramer, which is found in the lumen of synaptic vesicles of corresponding nerve cells, where it localizes to both the membrane and cytosol. DBH is induced by nerve growth factor and Insulin growth factor-1 and is regulated by intracellular second messengers protein kinase A, cyclic AMP, diacyl glycerol and Ca2+. Expression of DBH is transcriptionally mediated by Sp1, CREB and AP-1 proteins including c-Fos, c-Jun and JunD.
Applications
IHC-P
Positive Control
Human adrenal gland or adrenal pheochromocytoma.
Dilutions
IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment (around Amino Acids 200-400) of human DBH protein. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
DBH/7222
Isotype
IgG2
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
78 kDa / 84 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
dbh, DBM, Dopamine beta monooxygenase, Dopamine beta-hydroxylase (dopamine beta-monooxygenase), Dopamine beta-monooxygenase, DOPO_HUMAN, OTTHUMP00000022501, Soluble dopamine beta-hydroxylase
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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