Rabbit polyclonal antibody to DOK2 (phospho Tyr299).
Specificity
This antibody recognises docking protein 2 (DOK2), also known as dok-2 and downstream of tyrosine kinase 2, when phosphorylated at tyrosine 299. DOK2 belongs to the downstream of tyrosine kinase (Dok) family of adaptor proteins involved in receptor signaling.DOK2 is phosphorylated by Bcr-Abl, receptor tyrosine kinases and also cytoplasmIc protein tyrosine kinases (Gérard et al. 2004).
Applications
WB, IHC-P
Dilutions
IHC-P: 1:50 - 1:100, WB: 1:500 - 1:2,000
Reactivity
Human
Immunogen
Phospho-specific peptide corresponding to residues surrounding Tyr299 of human DOK2.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate
Unconjugated
Concentration
Lot Specific
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 50% Glycerol and 0.09% Sodium Azide
Storage
Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
General Notes
Rabbit anti DOK2 (pTyr299) antibody recognizes docking protein 2 (DOK2), also known as dok-2 and downstream of tyrosine kinase 2, when phosphorylated at tyrosine 299. DOK2 belongs to the downstream of tyrosine kinase (Dok) family of adaptor proteins involved in receptor signaling.DOK2 is phosphorylated by Bcr-Abl, receptor tyrosine kinases and also cytoplasmIc protein tyrosine kinases (Gérard et al. 2004).
Synonyms
Docking protein 2, Docking protein 2 56kDa, DOK 2, DOK R, DOK2_HUMAN, Downstream of tyrosine kinase 2, OTTHUMP00000161710, OTTHUMP00000224923, p56(dok 2), p56(dok-2), p56DOK, p56dok 2, p56dok2
