This antibody recognises CRM197 , a non-toxic mutant form of diphtheria toxin with an amino acid substitution at glycine-52 to glutamic acid.
Applications
ELISA
Reactivity
Bacterial
Immunogen
Purified diphtheria toxoid.
Host
Goat
Clonality
Polyclonal
Isotype
IgG
Conjugate
Unconjugated
Concentration
5 mg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.1% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Diphtheria toxin is an exotoxin secreted by various strains of Corynebacterium diphtheriae that is the cause of diphtheria. The active toxin is a single chain of 535 amino acids composed of 3 distinct structural/functional domains; and N-Terminal ADP-ribosyltransferase (catalytic domain); a region which facilitates the delivery of the catalytic domain across the cell membrane (transmembrane domain) and the eukaryotic cell receptor binding domain.
