Anti-ZC3H7A Antikörper [PCRP-ZC3H7A-1D6] (A278224)

Name: Anti-ZC3H7A Antibody [PCRP-ZC3H7A-1D6] - BSA and Azide free
Brand: Antibodies.com
SKU: A278224
Price: 525.0 USD
Availability: InStock

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$525

Monoklonal [PCRP-ZC3H7A-1D6] Maus Antikörper gegen ZC3H7A für ELISA, IP, Flow Cytometry und IF.

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Alternative Formats and ConjugatesAlternative Formats

Unconjugated

Versand

Versandkosten

$40

Vorlaufzeit

Lieferung in 4-6 Werktagen

Kontakt

Telefon

+1 (314) 370-6046

orders@antibodies.com

Garantien

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Stichworte:

Monospezifischer Antikörper

Produktdetails

Produktname

Anti-ZC3H7A Antibody [PCRP-ZC3H7A-1D6] - BSA and Azide free

Beschreibung

Mouse monoclonal [PCRP-ZC3H7A-1D6] antibody to ZC3H7A.

Spezifität

The zinc finger CCCH domain-containing protein 7A (ZC3H7A), also known as ZC3H7, HSPC055 or ZC3HDC7, is a 971 amino acid protein that contains a C3H1-type zinc finger domain, three C3H1-type zinc fingers and three TPR repeats. Belonging to the ZC3H12 family, ZC3H7A localizes to the nucleus. Existing as two alternatively spliced isoforms, ZC3H7A is encoded by a gene located on human chromosome 16p13.13. Chromosome 16 makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of RubinsteinTaybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn s disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene.

Anwendungen

ELISA, IP, Flow Cytometry, IF

Verdünnungen

IP: 1-2µg / 100-500µg proteins, Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml

Reaktivität

Human

Immunogen

Recombinant full-length human ZC3H7A protein.

Wirt

Mouse

Klonalität

Monoclonal

Klon

PCRP-ZC3H7A-1D6

Isotyp

IgG1

Konjugat

Unconjugated

Reinigung

Protein A/G chromatography.

Konzentration

1 mg/ml

Molekulargewicht

110 kDa

Produktform

Liquid

Formulierung

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Lagerung

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Allgemeine Hinweise

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-ZC3H7A Antibody [PCRP-ZC3H7A-1D6] (A277636).

Synonyme

HSPC055, ZC3H7, ZC3HDC7, Zinc finger CCCH domain containing protein 7A, zinc finger CCCH type containing 7, zinc finger CCCH type containing 7A, zinc finger CCCH type domain containing 7, zinc finger protein AY163807

Isotyp-Kontrollantikörper

Kompatible Sekundärantikörper

Haftungsausschluss

Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

Produktbilder (4)

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Figure 1: Flow Cytometry - Anti-ZC3H7A Antibody [PCRP-ZC3H7A-1D6] - BSA and Azide free (A278224)

Flow cytometric analysis of PFA-fixed HeLa cells using Anti-ZC3H7A Antibody [PCRP-ZC3H7A-1D6] followed by Goat Anti-Mouse IgG (CF® 488) (Blue). Isotype Control (Red).

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Figure 2: SDS-PAGE - Anti-ZC3H7A Antibody [PCRP-ZC3H7A-1D6] - BSA and Azide free (A278224)

SDS-PAGE analysis of Anti-ZC3H7A Antibody [PCRP-ZC3H7A-1D6] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.

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Figure 3: Immunofluorescence - Anti-ZC3H7A Antibody [PCRP-ZC3H7A-1D6] - BSA and Azide free (A278224)

Immunofluorescent analysis of PFA-fixed HeLa cells stained with Anti-ZC3H7A Antibody [PCRP-ZC3H7A-1D6] followed by Goat Anti-Mouse IgG (CF® 488) (Green). CF® 640A Phalloidin (Red).

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Figure 4: Anti-ZC3H7A Antibody [PCRP-ZC3H7A-1D6] - BSA and Azide free (A278224)

Analysis of protein array containing more than 19,000 full-length human proteins using Anti-ZC3H7A Antibody [PCRP-ZC3H7A-1D6]. Z-Score and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProt^TM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProt^TM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target; a MAb is considered to be specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.