Rekombinant Anti-VLDL Receptor Antikörper [rVLDLR/1337] (A277928)

Anti-VLDL Receptor Antibody [rVLDLR/1337]

Recombinant mouse monoclonal [rVLDLR/1337] antibody to VLDL Receptor.

VLDLR (very low density lipoprotein receptor) is a member of the LDL receptor gene family, which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDLR is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.

IHC-P

IHC-P: 1-2 µg/ml

Human, Rat

Recombinant fragment corresponding to the C terminal of human VLDLR.

Mouse

Monoclonal

rVLDLR/1337

IgG1

kappa

Protein A/G chromatography.

200 µg/ml

143-161 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-VLDL Receptor Antibody [rVLDLR/1337] - BSA and Azide free (A278516).

FLJ35024, Very low density lipoprotein receptor, Very low-density lipoprotein receptor, VLDL R, VLDL-R, VLDLR, VLDLRCH, VLDLR_HUMAN