Mouse monoclonal [DF1513] antibody to Transferrin Receptor.
Spezifität
This antibody recognises the human CD71 cell surface antigen, a ~190 kDa homodimeric glycoprotein expressed by proliferating cells. CD71 is also known as the transferrin receptor. Mutation of the TFRC gene has been implicated in the development of Immunodeficiency 46 (IMD46) a combined immunodeficiency characterized by early onset chronic diarrhea, recurrent infections and intermittent neutropenia and thrombocytopenia
Anwendungen
Flow Cytometry, IF
Verdünnungen
Flow Cytometry: 1:10 - 1:25, Use 10µl of the suggested working dilution to label 106 cells in 100µl.
Reaktivität
Human, Rhesus Monkey, Mustelid, Ferret
Immunogen
KGI cell line.
Wirt
Mouse
Klonalität
Monoclonal
Klon
DF1513
Isotyp
IgG1
Konjugat
Unconjugated
Reinigung
Protein A affinity chromatography of tissue culture supernatant.
Konzentration
1 mg/ml
Produktform
Liquid
Formulierung
Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.
Lagerung
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
Allgemeine Hinweise
Mouse anti Human CD71 antibody, clone DF1513 recognizes the human CD71 cell surface antigen, a ~190 kDa homodimeric glycoprotein expressed by proliferating cells. CD71 is also known as the transferrin receptor. Mutation of the TFRC gene has been implicated in the development of Immunodeficiency 46 (IMD46) a combined immunodeficiency characterized by early onset chronic diarrhea, recurrent infections and intermittent neutropenia and thrombocytopenia (Jabara et al. 2016)