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Anti-Transferrin Antikörper [TF/4799] (A315749)

$765

Monoklonal [TF/4799] Maus Antikörper gegen Transferrin für WB und IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-Transferrin Antibody [TF/4799]
Beschreibung
Mouse monoclonal [TF/4799] antibody to Transferrin.
Spezifität
Iron (Fe) is a tightly metabolically controlled mineral and growth factor present in all living cells. Iron not bound in erythrocyte hemoglobin is transported by transferrin (Tf), the iron transport protein of vertebrate serum. The transferrin protein contains two homologous domains, each of which contain an Fe-binding site. The majority of transferrin is synthesized in the liver and secreted into the blood, but it is also produced in lower amounts in testis and brain as well as in oligodendrocytes, where transferrin is an early marker of oligodendrocyte differentiation. From the blood, transferrin is internalized by erythroblasts and reticulocytes upon binding the transferrin receptor (TfR), also designated CD71, through a system of coated pits and vesicles. After Fe release, transferrin is returned to the extracellular medium, where it can be reused. Defects in the transferrin gene results in atransferrinemia, a rare autosomal recessive disorder characterized by microcytic anemia and iron loading.
Anwendungen
WB, IHC-P
Positivkontrolle
Human liver or hepatocellular carcinoma.
Verdünnungen
WB: 1-2 µg/ml, IHC: 1-2 µg/ml
Reaktivität
Human
Immunogen
Recombinant fragment (around Amino Acids 311-445) of human TF protein. The exact sequence is proprietary.
Wirt
Mouse
Klonalität
Monoclonal
Klon
TF/4799
Isotyp
IgG2
Leichte Ketten
kappa
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
200 µg/ml
Molekulargewicht
79 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyme
Apotransferrin, ATRAF, Atransferrinemia, Beta 1 metal binding globulin, Beta-1 metal-binding globulin, DKFZp781D0156, HEL S 71p, HELS71p, PRO1400, PRO1557, PRO2086, Serotransferrin, Serotransferrin precursor, Siderophilin, TF, TFQTL1, Transferin, TRFE_HUMAN
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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