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Rekombinant Anti-Topoisomerase II alpha Antikörper [TOP2A/6570R] (A278660)

Monoklonal [TOP2A/6570R] Kaninchen Antikörper gegen Topoisomerase II alpha für WB und IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-Topoisomerase II alpha Antibody [TOP2A/6570R] - BSA and Azide free
Beschreibung
Recombinant rabbit monoclonal [TOP2A/6570R] antibody to Topoisomerase II alpha.
Spezifität
The topoisomerase II-α isoform is a 170kDa nuclear protein and plays an important role in DNA synthesis and RNA transcription, as well as chromosomal segregation during mitosis. Topoisomerase II-α is reported to be a sensitive and specific marker of late S-, G2- & M-phases in transformed and developmentally regulated normal cells, and has been shown to be over-expressed in many human cancers. Decreased expression of Topoisomerase II-α is the predominant mechanism of resistance to several chemotherapeutic agents.
Anwendungen
WB, IHC-P
Verdünnungen
WB: 2-4 µg/ml, IHC-P: 1-2 µg/ml
Reaktivität
Human
Immunogen
Recombinant fragment, around amino acids 1,352-1,493, of human Topoisomerase II alpha. The exact sequence is proprietary.
Wirt
Rabbit
Klonalität
Monoclonal
Klon
TOP2A/6570R
Isotyp
IgG
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
1 mg/ml
Molekulargewicht
170 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Allgemeine Hinweise
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-Topoisomerase II alpha Antibody [TOP2A/6570R] (A278072).
Synonyme
alpha isozyme, ATP hydrolyzing DNA topoisomerase II alfa, DNA gyrase, DNA topoisomerase (ATP hydrolyzing), DNA topoisomerase 2 alpha, DNA topoisomerase 2-alpha, DNA topoisomerase II, DNA topoisomerase II 170 kD, DNA topoisomerase II alpha isozyme, DNA Topoisomerase2, TOP 2A, TOP2, TOP2A, TOP2A_HUMAN, Topoisomerase DNA II alpha 170kDa, TP2A
Isotyp-Kontrollantikörper
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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