Anti-TNFSF9 Antibody [CD137L/1547] (Biotin) (A251231)

Anti-TNFSF9 Antibody [CD137L/1547] (Biotin)

Mouse monoclonal [CD137L/1547] antibody to TNFSF9 (Biotin).

TNFSF9 / 4-1BBL is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9 / 4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9 / 4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. It has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine is required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.

Flow Cytometry, IF, IHC-P

Flow Cytometry: 2-4 µg/million cells, IF: 2-4 µg/ml, IHC-P: 2-4 µg/ml

Human

Recombinant full-length human CD137L protein.

Mouse

Monoclonal

IgG2a

kappa

Protein A/G chromatography.

100 µg/ml

27 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

4-1BB ligand, Tumor necrosis factor ligand superfamily member 9

This product is for research use only. It is not intended for diagnostic or therapeutic use.