Recombinant Anti-TLR2 Antibody [rTLR2/221] (A250150)

Anti-TLR2 Antibody [rTLR2/221]

Recombinant mouse monoclonal [rTLR2/221] antibody to TLR2.

This antibody reacts with human Toll-like receptor 2 (TLR2). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.

Human

This antibody is predicted to cross react with Monkey and Canine.

Recombinant full-length human TLR2 protein.

Mouse

Monoclonal

rTLR2/221

IgG1

kappa

Protein A/G chromatography.

200 µg/ml

90 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-TLR2 Antibody [rTLR2/221] - BSA and Azide free (A253330).

CD282, TIL4, Toll-like receptor 2, Toll/interleukin-1 receptor-like protein 4