Rekombinant Anti-TLE 1 Antikörper [TLE1/8007R] (A315735)

Anti-TLE 1 Antibody [TLE1/8007R]

Recombinant rabbit monoclonal [TLE1/8007R] antibody to TLE 1.

Key players in the Notch pathway are the TLE genes, which are human homologs of the Drosophila groucho gene. Groucho is a transcriptional repressor that plays a key role in neurogenesis, segmentation and sex determination. Transducin-like enhancer proteinTLE1 gene and is involved in control of hematopoiesis, neuronal, and terminal epithelial differentiation. Positive immunohistochemical nuclear staining with anti-TLE-1 has been shown to be a useful addition to an IHC panel when differentiating synovial sarcoma from other soft tissue malignancies.

IHC-P

HeLa, HepG2 or Jurkat cells. Human endometrium carcinoma or sarcomas.

IHC: 1-2 µg/ml

Human

Recombinant human TLE1 fragment (aa 175-338). The exact sequence is proprietary.

Rabbit

Monoclonal

TLE1/8007R

IgG

Unconjugated

Protein A/G chromatography.

200 µg/ml

83 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

E(Sp1) homolog, Enhancer of split groucho 1, Enhancer of split groucho like protein 1, Enhancer of split groucho-like protein 1, ESG, ESG1, GRG1, TLE1, TLE1_HUMAN, Transducin like enhancer of split 1, Transducin like enhancer of split 1 (E(sp1) homolog Drosophila), Transducin like enhancer of split 1 homolog of Drosophila E(sp1), Transducin like enhancer protein 1, Transducin-like enhancer protein 1