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Anti-Thyroglobulin Antikörper [TGB04 + TGB05] (A253288)

Oligoclonal [TGB04 + TGB05] Maus Antikörper gegen Thyroglobulin für Flow Cytometry und IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-Thyroglobulin Antibody [TGB04 + TGB05] - BSA and Azide free
Beschreibung
Mouse monoclonal [TGB04 + TGB05] antibody to Thyroglobulin.
Spezifität
Thyroglobulin is a 660kDa dimeric pre-protein with mutiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable marker to differentiate between primary thyroid and lung neoplasms.
Anwendungen
Flow Cytometry, IHC-P
Verdünnungen
Flow Cytometry: 0.5-1 µg/million cells, IHC-P: 1-2 µg/ml
Reaktivität
Human, Mouse, Rat
Immunogen
Human thyroid follicular cells.
Wirt
Mouse
Klonalität
Oligoclonal
Klon
TGB04 + TGB05
Isotyp
IgG1, kappa + IgG1, kappa
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
1 mg/ml
Molekulargewicht
660 kDa (dimeric Form)
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Allgemeine Hinweise

Please note, this product is an oligoclonal antibody; it is a cocktail of monoclonal antibodies that have been carefully selected. Oligoclonal antibodies not only have the specificity and batch-to-batch consistency of a monoclonal antibody, but they also have the advantage of the sensitivity of a polyclonal antibody due to their ability to recognize multiple epitopes on an antigen.

This oligoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-Thyroglobulin Antibody [TGB04 + TGB05] (A250108).

Synonyme
AITD 3, AITD3, hTG, TDH3, Tg, TGN, THYG_HUMAN
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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