Recombinant Anti-Thrombomodulin Antibody [THBD/8188R] (A315725)

Anti-Thrombomodulin Antibody [THBD/8188R]

Recombinant rabbit monoclonal [THBD/8188R] antibody to Thrombomodulin.

It recognizes a protein of 75kDa, identified as Thrombomodulin. Thrombomodulin is a transmembrane glycoprotein with natural anticoagulant properties. It is normally expressed by a restricted number of cells, such as endothelial and mesothelial cells. In addition, synovial lining and syncytio-trophoblasts of placenta also express thrombomodulin. This protein is present in almost all of benign vascular tumors and majority of malignant vascular tumors (Kaposi s sarcoma, angiosarcoma, and epithelioid hemangioendothelioma). Hence, anti-thrombomodulin serves as a sensitive marker for lymphatic endothelial cells and their tumors. Recently, thrombomodulin antibody has been used for mesothelial cells and malignant mesotheliomas.

Placenta, Angiosarcoma, Bladder or Cervical Carcinoma.

IHC: 1-2 µg/ml

Human

Recombinant full-length human Thrombomodulin (CD141) protein.

Rabbit

Monoclonal

THBD/8188R

kappa

Protein A/G chromatography.

200 µg/ml

~100 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

CD141, Fetomodulin, THBD, THRM, TM