Anti-TEM7 Antibody (A283163)

Anti-TEM7 Antibody

Rabbit polyclonal antibody to TEM7.

This antibody recognises human Tumour endothelial marker 7, also known as TEM7, a 55.8 kDa protein belonging to the plexin family.TEM7 is strongly expressed in endothelial cells from colorectal cancer and from primary cancers of the lung, liver, brain, breast and pancreas. High expression of TEM7 is associated with metastasis and poor survival of patients with osteogenic sarcoma.There appear to be at least four isoforms of TEM7 which include membrane bound, secreted and intracellular forms. TEM7 is not detectable in endothelial cells from normal tissues.

WB, IHC-P

IHC-P 1: 2.5 µg/ml, WB: 0.5 - 1 µg/ml

Human, Mouse, Rat

A peptide corresponding to 16 amino acids near the center of human TEM7.

Rabbit

Polyclonal

IgG

Approximately 56 kDa in rat liver cell lysates.

Liquid

Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Rabbit anti Human TEM7 antibody recognises human Tumour endothelial marker 7, also known as TEM7, a 55.8 kDa protein belonging to the plexin family. TEM7 is strongly expressed in endothelial cells from colorectal cancer and from primary cancers of the lung, liver, brain, breast and pancreas. High expression of TEM7 is associated with metastasis and poor survival of patients with osteogenic sarcoma. There appear to be at least four isoforms of TEM7 which include membrane bound, secreted and intracellular forms. TEM7 is not detectable in endothelial cells from normal tissues.

Plexin domain-containing protein 1, PLXDC1, TEM3, Tumor endothelial marker 3, Tumor endothelial marker 7