Recombinant mouse monoclonal [rSYP/8807] antibody to Synaptophysin.
Spezifität
This recombinant mouse monoclonal antibody recognizes a protein of 38kDa that is identified as synaptophysin. It is an N-glycosylated integral membrane protein found in neurons and endocrine cells. Synaptophysin contains four transmembrane domains and may function as a gap junction-like channel.This antibody identifies normal neuroendocrine cells and neuroendocrine neoplasms. Diffuse, finely granular, cytoplasmic staining is observed, which probably correlates with the distribution of the antigen within neurosecretory vesicles. Synaptophysin is an independent, broad-range marker of neural and neuroendocrine differentiation.
Anwendungen
IHC-P
Positivkontrolle
HepG2, HeLa or Y79 cells. Human pancreas, cerebellum or pheochromocytoma.
Verdünnungen
IHC: 1-2 µg/ml
Reaktivität
Human
Immunogen
Recombinant fragment (around Amino Acids 224-313) of human Synaptophysin (SYP) protein. The exact sequence is proprietary.
Wirt
Mouse
Klonalität
Monoclonal
Klon
rSYP/8807
Isotyp
IgG2b
Leichte Ketten
kappa
Konjugat
Unconjugated
Reinigung
Protein A/G chromatography.
Konzentration
200 µg/ml
Molekulargewicht
38 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyme
Major synaptic vesicle protein p38, MRX96, MRXSYP, Syn p38, Syp, SYPH, SYPH_HUMAN, SypI