Anti-Synaptophysin Antibody [rSYP/6856] - BSA and Azide free
Beschreibung
Recombinant mouse monoclonal [rSYP/6856] antibody to Synaptophysin.
Spezifität
This antibody recognizes a protein of 38kDa that is identified as synaptophysin. It is an N-glycosylated integral membrane protein found in neurons and endocrine cells. Synaptophysin contains four transmembrane domains and may function as a gap junction-like channel. This antibody identifies normal neuroendocrine cells and neuroendocrine neoplasms. Diffuse, finely granular, cytoplasmic staining is observed, which probably correlates with the distribution of the antigen within neurosecretory vesicles. Synaptophysin is an independent, broad-range marker of neural and neuroendocrine differentiation.
Anwendungen
IHC-P
Verdünnungen
IHC-P: 1-2 µg/ml
Reaktivität
Human
Immunogen
Recombinant fragment, around amino acids 224-313, of human Synaptophysin protein. The exact sequence is proprietary.
Wirt
Mouse
Klonalität
Monoclonal
Klon
rSYP/6856
Isotyp
IgG1
Leichte Ketten
kappa
Konjugat
Unconjugated
Reinigung
Protein A/G chromatography.
Konzentration
1 mg/ml
Molekulargewicht
38 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Immunohistochemical analysis of formalin-fixed, paraffin-embedded human brain tissue using Anti-Synaptophysin Antibody [rSYP/6856] at 2µg/ml. Inset: PBS instead of the primary antibody. Secondary antibody negative control.
SDS-PAGE analysis of Anti-Synaptophysin Antibody [rSYP/6856] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.
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