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Anti-Steroidogenic Factor 1 Antikörper [NR5A1/3420] (A277619)

Monoklonal [NR5A1/3420] Maus Antikörper gegen Steroidogenic Factor 1 für IHC-P.

Alternative Formats and ConjugatesAlternative Formats

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Vorlaufzeit
Lieferung in 4-6 Werktagen
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+1 (314) 370-6046
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Email
orders@antibodies.com
Produktname
Anti-Steroidogenic Factor 1 Antibody [NR5A1/3420]
Beschreibung
Mouse monoclonal [NR5A1/3420] antibody to Steroidogenic Factor 1.
Spezifität
The protein encoded by this gene is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect. Steroidogenic Factor 1 (SF-1) is considered an orphan nuclear receptor that belongs to subfamily 5. It was found to be a regulator of steroidogenic enzyme gene expression. Oxysterols are suggested as its ligands. It is expressed in all steroidogenic tissues, including the adrenal cortex, testicular Sertoli cells, and Leydig cells, ovarian theca, hypothalamus, and anterior pituitary. SF-1 plays an important role in adrenal and gonadal development. SF-1 is highly valuable marker to determine the adrenocortical origin of an adrenal mass.
Anwendungen
IHC-P
Verdünnungen
IHC-P: 1-2 µg/ml
Reaktivität
Human
Immunogen
Recombinant fragment, around amino acids 220-461, of human Steroidogenic Factor 1 protein. The exact sequence is proprietary.
Wirt
Mouse
Klonalität
Monoclonal
Klon
NR5A1/3420
Isotyp
IgG2b
Leichte Ketten
kappa
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
200 µg/ml
Molekulargewicht
53 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Allgemeine Hinweise
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Steroidogenic Factor 1 Antibody [NR5A1/3420] - BSA and Azide free (A278207).
Synonyme
AD4BP, Adrenal 4 binding protein, Adrenal 4-binding protein, ELP, FTZ 1, FTZ1, FTZF 1, FTZF1, Fushi tarazu factor (Drosophila) homolog 1, Fushi tarazu factor homolog 1, hSF 1, NR5A1, Nuclear receptor AdBP4, Nuclear receptor subfamily 5 group A member 1, POF7, SF 1, SF-1, SF1, SPGF8, SRXY3, Steroid hormone receptor Ad4BP, Steroidogenic factor 1 nuclear receptor, STF 1, STF-1, STF1, STF1_HUMAN
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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