Anti-STAT1 (phospho Tyr701) Antibody (A283678)

Anti-STAT1 (phospho Tyr701) Antibody

Rabbit polyclonal antibody to STAT1 (phospho Tyr701).

This antibody recognises STAT1, also known as transcription factor ISGF-3 components p91/p84, when phosphorylated at tyrosine 701. STAT1 is part of the transcription factor STAT family of proteins. STAT proteins form homo- or hetero-dimers once phosphorylated by receptor associated kinases. Following dimerization STAT proteins then translocate to the cell nucleus. Phosphorylation at tyrosine 701 induces dimerization and activates the transcriptional activity of STAT1.

WB: 1:500 - 1:1,000

Human, Mouse, Rat

Phospho-specific peptide corresponding to residues surrounding Tyr701 of human STAT1.

Rabbit

Polyclonal

IgG

Liquid

Supplied in Phosphate Buffered Saline with 0.05% ProClin 300 and 50% Glycerol.

Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.

Rabbit anti STAT1 (pTyr701) antibody recognizes STAT1, also known as transcription factor ISGF-3 components p91/p84, when phosphorylated at tyrosine 701. STAT1 is part of the transcription factor STAT family of proteins. STAT proteins form homo- or hetero-dimers once phosphorylated by receptor associated kinases. Following dimerization STAT proteins then translocate to the cell nucleus. Phosphorylation at tyrosine 701 induces dimerization and activates the transcriptional activity of STAT1 (Wenta et al. 2008).

Signal transducer and activator of transcription 1-alpha/beta, Transcription factor ISGF-3 components p91/p84