+1 (314) 370-6046 oderKontakt

Anti-Spastin Antikörper [Sp 3G11-1] (A253201)

Monoklonal [Sp 3G11-1] Maus Antikörper gegen Spastin für ELISA, IF, WB und IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-Spastin Antibody [Sp 3G11-1] - BSA and Azide free
Beschreibung
Mouse monoclonal [Sp 3G11-1] antibody to Spastin.
Spezifität
The AAA protein family members share an ATPase domain and have roles in various cellular processes including intracellular motility, membrane trafficking, proteolysis, protein folding and organelle biogenesis. Spastin, a member of the AAA protein family, is a 616 amino acid protein and is involved in the function or assembly of nuclear protein complexes. The Spastin protein is expressed ubiquitously and localizes to the nucleus and the cytoplasm, where it may also be involved in microtubule dynamics. Mutations in the Spastin gene (SPAST, SPG4) cause the most common form of spastic paraplegia 4, an autosomal dominant form of hereditary spastic paraplegia (HSP). HSPs comprise a group of inherited neurological disorders characterized by spastic lower extremity weakness due to a length-dependent, retrograde axonopathy of corticospinal motor neurons. SPAST-specific mutations account for approximately 40% of all autosomal dominant HSPs.
Anwendungen
ELISA, IF, WB, IHC-P
Verdünnungen
IF: 1-2 µg/ml, WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reaktivität
Human, Mouse, Rat
Immunogen
Recombinant full-length human Spastin protein.
Wirt
Mouse
Klonalität
Monoclonal
Klon
Sp 3G11-1
Isotyp
IgG2a
Leichte Ketten
kappa
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
1 mg/ml
Molekulargewicht
52 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Allgemeine Hinweise
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-Spastin Antibody [Sp 3G11-1] (A250021).
Synonyme
ADPSP, FSP 2, FSP2, KIAA1083, Spast, Spastic paraplegia 4, spastic paraplegia 4 (autosomal dominant; spastin), SPG 4, SPG4, SPG4 gene
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

Alternative Produkte zum Anti-Spastin Antikörper [Sp 3G11-1] (A253201)

Oben