Rekombinant Anti-SOX2 Antikörper [rSOX2/1791] (A253184)

Name: Anti-SOX2 Antibody [rSOX2/1791] - BSA and Azide free
Brand: Antibodies.com
SKU: A253184
Price: 525.0 USD
Availability: InStock

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$525

Monoklonal [rSOX2/1791] Maus Antikörper gegen SOX2 für IHC.

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Alternative Formats and ConjugatesAlternative Formats

Unconjugated

Versand

Versandkosten

$40

Vorlaufzeit

Lieferung in 4-6 Werktagen

Kontakt

Telefon

+1 (314) 370-6046

orders@antibodies.com

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Stichworte:

Rekombinant Antikörper iPSCs Marker Neural Stem Cell Marker Neuroepithelial Marker Radial Glia Marker

Produktdetails

Produktname

Anti-SOX2 Antibody [rSOX2/1791] - BSA and Azide free

Beschreibung

Recombinant mouse monoclonal [rSOX2/1791] antibody to SOX2.

Spezifität

SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression. Reportedly, SOX2 is associated with aggressive phenotypes of breast, head and neck, gastric, colorectal, bladder, and small cell lung cancers. However, SOX2 is expressed in a high percentage of lung squamous cell carcinomas and has been shown to be an independent favorable prognostic marker.

Anwendungen

IHC

Verdünnungen

IHC-P: 1-2 µg/ml

Reaktivität

Human, Mouse

Immunogen

Recombinant fragment, within amino acids 176-305, of human SOX2 protein. The exact sequence is proprietary.

Wirt

Mouse

Klonalität

Monoclonal

Klon

rSOX2/1791

Isotyp

IgG1

Leichte Ketten

kappa

Konjugat

Unconjugated

Reinigung

Protein A/G chromatography.

Konzentration

1 mg/ml

Molekulargewicht

34 kDa

Produktform

Liquid

Formulierung

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Lagerung

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Allgemeine Hinweise

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-SOX2 Antibody [rSOX2/1791] (A250004).

Synonyme

ANOP3, cb236, Delta EF2a, lcc, MCOPS3, MGC148683, MGC2413, RGD1565646, Sex determining region Y box 2, SOX 2, SOX2_HUMAN, SRY (sex determining region Y) box 2, SRY box containing gene 2, SRY related HMG box 2, SRY related HMG box gene 2, SRY-box 2, Transcription factor SOX 2, Transcription factor SOX-2, ysb

Isotyp-Kontrollantikörper

Kompatible Sekundärantikörper

Haftungsausschluss

Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

Produktbilder (2)

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Figure 1: Immunohistochemistry - Anti-SOX2 Antibody [rSOX2/1791] - BSA and Azide free (A253184)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human cervix using Anti-SOX2 Antibody [rSOX2/1791].

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Figure 2: SDS-PAGE - Anti-SOX2 Antibody [rSOX2/1791] - BSA and Azide free (A253184)

SDS-PAGE analysis of Anti-SOX2 Antibody [rSOX2/1791] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.