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Rekombinant Anti-SOX11 Antikörper [SOX11/3235R] (A253200)

Monoklonal [SOX11/3235R] Kaninchen Antikörper gegen SOX11 für IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-SOX11 Antibody [SOX11/3235R] - BSA and Azide free
Beschreibung
Recombinant rabbit monoclonal [SOX11/3235R] antibody to SOX11.
Spezifität
This antibody recognizes a protein of ~47kDa, identified as SOX11. This MAb is highly specific and does not cross-react with other members of the SOX-family. Mantle cell lymphoma (MCL) accounts for 5% to 10% of mature B-cell neoplasms and is an aggressive disease genetically characterized by overexpression of Cyclin D1. Cyclin D1 overexpression is the hallmark of MCL. However, approximately 5%-10% of MCLs lack Cyclin D1 expression and may be misdiagnosed. Almost all Cyclin D1-positive as well as Cyclin D1-negative MCL, show overexpression of SOX-11. The detection of this transcription factor is a useful biomarker for identifying true cyclin D1-negative MCL.
Anwendungen
IHC-P
Verdünnungen
IHC-P: 2-4 µg/ml
Reaktivität
Human
Immunogen
Recombinant fragment, around amino acids 300-400, of human SOX11 protein. The exact sequence is proprietary.
Wirt
Rabbit
Klonalität
Monoclonal
Klon
SOX11/3235R
Isotyp
IgG
Leichte Ketten
kappa
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
1 mg/ml
Molekulargewicht
47 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Allgemeine Hinweise
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-SOX11 Antibody [SOX11/3235R] (A250020).
Synonyme
MRD27, SOX11_HUMAN, SRY (sex determining region Y) box 11, SRY related HMG box gene 11, SRY-box 11, Transcription factor SOX-11
Isotyp-Kontrollantikörper
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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