Somatostatin is a regulatory hormone that is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to highaffinity G protein-coupled somatostatin receptors. This cyclic tetradecapeptide inhibits the secretion of many important hormones, including somatotropin (also designated growth hormone, or GH), Insulin and glucagon. Somatostatin is found in both the hypothalamus and pancreas. Somatostatin is thought to be involved in the regulation of Insulin synthesis. The hormone somatostatin has active 14 amino acid and 28 amino acid forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. In the cerebellum, Somatostatin-14 and Somatostatin-28 are highly expressed at birth and in the adult stage, respectively. Somatostatin affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells. The gene encoding Somatostatin maps to human chromosome 3q27.3.

Anwendungen

IHC-P

Positivkontrolle

Human pancreas.

Verdünnungen

IHC: 1-2 µg/ml

Reaktivität

Human

Immunogen

Recombinant fragment of human SST protein. The exact sequence is proprietary.

Wirt

Rabbit

Klonalität

Monoclonal

Klon

SST/7200R

Isotyp

IgG

Leichte Ketten

kappa

Konjugat

Unconjugated

Reinigung

Protein A/G chromatography.

Konzentration

200 µg/ml

Molekulargewicht

17 kDa

Produktform

Liquid

Formulierung

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Lagerung

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Synonyme

Growth hormone release inhibiting factor, Growth hormone release-inhibiting factor, Prepro somatostatin, SMST, SMS_HUMAN, Somatostatin 14, Somatostatin 28, Somatostatin-14, SST

Isotyp-Kontrollantikörper

Kompatible Sekundärantikörper

Haftungsausschluss

Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.