+1 (314) 370-6046 oderKontakt

Anti-SNF5 Antikörper [SMARCB1/3984] (A278382)

Monoklonal [SMARCB1/3984] Maus Antikörper gegen SNF5 für IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-SNF5 Antibody [SMARCB1/3984] - BSA and Azide free
Beschreibung
Mouse monoclonal [SMARCB1/3984] antibody to SNF5.
Spezifität
The INI-1 gene, which encodes a functionally uncharacterized protein component of the hSWI/SNF chromatin remodeling complex, is often mutated or deleted in malignant rhabdoid tumor (MRT). Two isoforms of INI-1, that differ by the variable inclusion of amino acids, potentially are produced by differential RNA splicing. The morphology of MRTs can present challenges in differential diagnosis. The overall survival of MRTs relative to its potential mimics (medulloblastoma, supratentorial primitive neuroectodermal tumors (sPNETs) is quite low, and thus differentiation from these other tumors is desirable. Lack of nuclear labeling by anti-INI-1 is characteristic of MRT. The majority of medulloblastomas and sPNETs are labeled by anti-INI-1. MRTs also originate from the kidney and soft tissues.
Anwendungen
IHC-P
Verdünnungen
IHC-P: 1-2 µg/ml
Reaktivität
Human
Immunogen
Recombinant fragment, around amino acids 65-184, of human SNF5 protein. The exact sequence is proprietary.
Wirt
Mouse
Klonalität
Monoclonal
Klon
SMARCB1/3984
Isotyp
IgG2b
Leichte Ketten
kappa
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
1 mg/ml
Molekulargewicht
47 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Allgemeine Hinweise
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-SNF5 Antibody [SMARCB1/3984] (A277794).
Synonyme
BAF47, BRG1-associated factor 47, hSNF5, INI1, Integrase interactor 1 protein, Malignant rhabdoid tumor suppressor, RDT, RTPS1, Sfh1p, SMARCB1, SNF5 homolog, SNF5L1, SNF5_HUMAN, Snr1, Sucrose nonfermenting yeast homolog like 1, SWI/SNF complex component SNF5, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1, SWI10, Transcription factor TYE4, Transcription regulatory protein SNF5, TYE4
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

Alternative Produkte zum Anti-SNF5 Antikörper [SMARCB1/3984] (A278382)

Oben