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Anti-Siglec 7 Antikörper [S7.7] (PE) (A281725)

$515

Monoklonal [S7.7] Maus Antikörper gegen Siglec 7 (PE) für Flow Cytometry.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-Siglec 7 Antibody [S7.7] (PE)
Beschreibung
Mouse monoclonal [S7.7] antibody to Siglec 7 (PE).
Spezifität
This antibody recognises human Sialic acid-binding Ig-like lectin 7, otherwise known as CD328, a putative adhesion molecule and member of the Ig superfamily, predominantly expressed by both resting and activated natural killer (NK) cells, and also at lower levels by monocytes, granulocytes, monocyte-derived macrophages and dendritic cells, and a small population of CD8+ memory T cells. Classed as a CD33-related Siglec, Siglec-7 preferentially binds to glycoconjugates containing alpha-2,3- or alpha-2,6-linked sialic acid, and acts as a novel inhibitory receptor for NK cells, mediating the inhibition of NK cell cytotoxicity, and implicated in the regulation of NK cell and T cell activation, and hematopoiesis. Mouse anti Human Siglec-7 antibody, cloneS7.7 is a blocking antibody , and has been shown to recognize Siglec-7 in Rhesus monkey.
Anwendungen
Flow Cytometry
Verdünnungen
Flow Cytometry: Neat, Use 10µl of the suggested working dilution to label 106 cells.
Reaktivität
Human, Rhesus Monkey
Immunogen
Siglec-7 3T3 transfected cells.
Wirt
Mouse
Klonalität
Monoclonal
Klon
S7.7
Isotyp
IgG1
Konjugat

PE

Excitation: 565nm, Emission: 578nm

Reinigung
Protein G affinity chromatography of tissue culture supernatant.
Konzentration
Reconstitution dependent.
Produktform
Lyophilized
Rekonstitution
Reconstitute with 1 ml of distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Gently mix after reconstitution.
Formulierung
Supplied in Phosphate Buffered Saline with 1% BSA, 5% Sucrose, and 0.09% Sodium Azide.
Lagerung
Lyophilized: Store at 4°C. Reconstituted: Store undiluted at 4°C. Do not freeze! This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
Allgemeine Hinweise
Mouse anti Human Siglec-7 antibody, cloneS7.7 recognizes human Sialic acid-binding Ig-like lectin 7, otherwise known as CD328, a putative adhesion molecule and member of the Ig superfamily, predominantly expressed by both resting and activated natural killer (NK) cells, and also at lower levels by monocytes, granulocytes, monocyte-derived macrophages and dendritic cells, and a small population of CD8+ memory T cells. Classed as a CD33-related Siglec, Siglec-7 preferentially binds to glycoconjugates containing alpha-2,3- or alpha-2,6-linked sialic acid, and acts as a novel inhibitory receptor for NK cells, mediating the inhibition of NK cell cytotoxicity, and implicated in the regulation of NK cell and T cell activation, and hematopoiesis. Mouse anti Human Siglec-7 antibody, cloneS7.7 is a blocking antibody (Avril et al. 2006), and has been shown to recognize Siglec-7 in Rhesus monkey (Jaroenpool et al. 2007).
Synonyme
Adhesion inhibitory receptor molecule 1, Adhesion inhibitory receptor molecule 1, siglec 7, AIRM 1, AIRM-1, AIRM1, CD328, CD328 antigen, CDw328, D siglec, D-siglec, HLDA 8, p75, p75/AIRM1, QA79, QA79 membrane protein, Sialic acid binding Ig like lectin 7, Sialic acid binding immunoglobulin like lectin 7, Sialic acid-binding Ig-like lectin 7, SIGL7_HUMAN, Siglec-7, SIGLEC19P, SIGLEC7, SIGLECP2
Isotyp-Kontrollantikörper
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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