Anti-Semaphorin 4D Antibody [133-1C6] - BSA and Azide free (A254298)

Anti-Semaphorin 4D Antibody [133-1C6] - BSA and Azide free

Mouse monoclonal [133-1C6] antibody to Semaphorin 4D.

This antibody recognizes a homodimeric protein comprised of 50kDa subunits, identified as CD100 (Workshop VI; Code N-L026). It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation.

Flow Cytometry, IF

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml

Human, Baboon

This antibody does not react with Horse.

PHA stimulated human peripheral blood lymphocytes.

Mouse

Monoclonal

133-1C6

kappa

1 mg/ml

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-Semaphorin 4D Antibody [133-1C6] (A248144).