Anti-S100A2 Antibody [CPTC-S100A2-2] - BSA and Azide free
Beschreibung
Mouse monoclonal [CPTC-S100A2-2] antibody to S100A2.
Spezifität
S100A2 belongs to the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100A2 may function as a modulator against excess calcium accumulation in normal human mammary epithelial cells and also have a role in suppressing tumor cell growth. This protein may have a tumor suppressor function. Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer. Cytoplasmic overexpression may also be of prognostic significance when observed in oral cancer patients, and the S100A2 has also been identified as significantly down-regulated in gastric cancer.
CAN19, MGC111539, Protein S 100L, Protein S-100L, Protein S100 A2, Protein S100-A2, Protein S100L, S100 A2, S100 alpha 2, S100 calcium binding protein A2, S100 calcium-binding protein A2, S100L, S10A2_HUMAN
Immunofluorescent analysis of A549 cells stained with Anti-S100A2 Antibody [CPTC-S100A2-2] followed by Goat Anti-Mouse IgG (CF® 488) (Green). The nuclear counterstain is RedDot (Red).
Flow cytometric analysis of trypsinised HeLa cells using Anti-S100A2 Antibody [CPTC-S100A2-2] followed by Goat Anti-Mouse IgG (CF® 488) (Blue). Isotype Control (Red).
Analysis of protein array containing more than 19,000 full-length human proteins using Anti-S100A2 Antibody [CPTC-S100A2-2]. Z-Score and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target; a MAb is considered to be specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.