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Anti-RNA Polymerase II CTD repeat YSPTSPS (phospho Ser5) Antikörper [CTD 8A7] (A254333)

Monoklonal [CTD 8A7] Maus Antikörper gegen RNA Polymerase II CTD repeat YSPTSPS (phospho Ser5) für Flow Cytometry, IF, WB und IHC-P.

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Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-RNA Polymerase II CTD repeat YSPTSPS (phospho Ser5) Antibody [CTD 8A7] - BSA and Azide free
Beschreibung
Mouse monoclonal [CTD 8A7] antibody to RNA Polymerase II CTD repeat YSPTSPS (phospho Ser5).
Spezifität
RNA polymerase II (Pol II) is an enzyme that is composed of 12 subunits and is responsible for the transcription of protein-coding genes. Transcription initiation requires Pol II-mediated recruitment of transcription machinery to a target promoter, thereby allowing transcription to begin. The largest subunit of Pol II (referred to as RPB1 or RPB205) is a 1,840 amino acid protein that contains one C2H2-type zinc finger and a C-terminal domain comprised of several heptapeptide repeats. Although Pol II function requires the cooperation of all twelve subunits, the largest subunit conveys Pol II catalytic activity and, together with the second largest subunit, forms the active center of the Pol II enzyme. Additionally, the large subunit participates in forming the DNA-binding domain of Pol II, a groove that is necessary for transcription of the DNA template. Without proper function of the large subunit, mRNA synthesis and subsequent transcription elongation cannot occur.
Anwendungen
Flow Cytometry, IF, WB, IHC-P
Verdünnungen
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reaktivität
Human, Saccharomyces cerevisiae
Immunogen
Ten repeats of synthetic peptide YSPTSPS using chemically synthesized phospho Ser5.
Wirt
Mouse
Klonalität
Monoclonal
Klon
CTD 8A7
Isotyp
IgM
Leichte Ketten
kappa
Konjugat

Unconjugated

Konzentration
1 mg/ml
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Allgemeine Hinweise
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-RNA Polymerase II CTD repeat YSPTSPS (phospho Ser5) Antibody [CTD 8A7] (A251056).
Synonyme
DNA directed RNA polymerase II A, DNA-directed RNA polymerase II largest subunit RNA polymerase II 220 kd subunit, DNA-directed RNA polymerase II subunit A, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase III largest subunit, hRPB220, hsRPB1, POLR2, Polr2a, POLRA, Polymerase (RNA) II (DNA directed) polypeptide A, Polymerase (RNA) II (DNA directed) polypeptide A 220kDa, RNA polymerase II subunit B1, RNA-directed RNA polymerase II subunit RPB1, RPB1, RPB1_HUMAN, RPBh1, RpIILS, RPO2, RPOL2
Isotyp-Kontrollantikörper
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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