ED50: 10 ng/ml, as determined by its ability to abolish the binding of iodinated VEGF to solid surfaces or cell surfaces, corresponding to a specific activity of 100,000 IU/mg. In a 13 day CAM-assay sVEGFR-1 is able to inhibit VEGF stimulated sprouting of capillaries at 30 pM.

Reinheit

>90% as determined by RP-HPLC and SDS-PAGE.

Produktform

Lyophilized

Konzentration

1mg/ml

Formulierung

Lyophilized without additives.

Lagerung

Shipped at ambient temperature. Lyophilized: Short term (3 weeks) store at 25°C. Long term store desiccated below -18°C. Reconstituted: Short term (2-7 days) store at 4°C. Long term store below -18°C, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid freeze/thaw cycles.

Synonyme

EC 2.7.10.1, FLT, FLT 1, Flt-1, FLT1, Fms like tyrosine kinase 1, Fms related tyrosine kinase 1, Fms related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor), Fms related tyrosine kinase 1 vascular endothelial growth factor/vascular permeability factor receptor, Fms-like tyrosine kinase 1, FRT, Soluble VEGF receptor 1 14, Soluble VEGFR1 variant 2, Soluble VEGFR1 variant 21, Tyrosine protein kinase FRT, Tyrosine protein kinase receptor FLT, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular endothelial growth factor receptor 1, Vascular endothelial growth factor vascular permeability factor receptor, Vascular endothelial growth factor/vascular permeability factor receptor, Vascular permeability factor receptor, Vascular permeability factor receptor 1, VEGFR 1, VEGFR-1, VEGFR1, VGFR1_HUMAN

Haftungsausschluss

Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.