The biological activity was determined by measuring the dose dependent mobilization of intracellular calcium (calcium flux) with human THP-1 cells. Significant calcium mobilization is observed with 500 ng/ml of recombinant human MCP-2. Human MCP-2 also induces dose dependent chemotaxis of human THP-1 cells with an ED50=30-100 ng/ml corresponding to a specific activity of 10,000-33,334 IU/mg.

Reinheit

>95% as determined by RP-HPLC and SDS-PAGE.

Produktform

Lyophilized

Konzentration

1mg/ml

Formulierung

Lyophilized without additives.

Lagerung

Shipped at ambient temperature. Lyophilized: Short term (3 weeks) store at 25°C. Long term store desiccated below -18°C. Reconstituted: Short term (2-7 days) store at 4°C. Long term store below -18°C, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid freeze/thaw cycles.

Synonyme

C C motif chemokine 8, CCL 8, Ccl8, CCL8_HUMAN, Chemokine (C C motif) ligand 8, Chemokine ligand 8, HC14, MCP 2, MCP-2, MCP-2(6-76), Monocyte chemoattractant protein 2, Monocyte chemotactic protein 2, SCYA10, SCYA8, Small inducible cytokine A8, Small inducible cytokine subfamily A (Cys Cys) member 8, Small-inducible cytokine A8

Haftungsausschluss

Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.