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Rekombinant Anti-RCAS1 Antikörper [rEBAG9/7264] (A315544)

$765

Monoklonal [rEBAG9/7264] Maus Antikörper gegen RCAS1 für IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-RCAS1 Antibody [rEBAG9/7264]
Beschreibung
Recombinant mouse monoclonal [rEBAG9/7264] antibody to RCAS1.
Spezifität
EBAG9, also known as RCAS1, is an estrogen-transcribed protein. Soluble and membranous RCAS1 proteins may play a role in the immune escape of tumor cells by promoting T lymphocyte inhibition of growth and apoptosis. RCAS1 is expressed in a wide variety of cancers, including uterine, ovarian, and lung cancer cells, and acts as a ligand for a putative receptor present on peripheral lymphocytes. RCAS1 is highly expressed not only in cancer cells but also in non-tumor bile duct cells subject to immune attack. RCAS1 inhibits the in vitro growth of receptor-expressing cells and induces apoptosis, contributing to the ability of tumor cells to evade host immune surveillance. High expression of RCAS1 significantly correlates with tumor progression and with poor outcome for many cancer patients.
Anwendungen
IHC-P
Positivkontrolle
MCF-7, Jurkat or HEK-293 cell lysates. Human skeletal muscle tissue.
Verdünnungen
IHC: 1-2 µg/ml
Reaktivität
Human
Immunogen
Recombinant full-length human EBAG9 protein.
Wirt
Mouse
Klonalität
Monoclonal
Klon
rEBAG9/7264
Isotyp
IgG1
Leichte Ketten
kappa
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
200 µg/ml
Molekulargewicht
32 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyme
BAG9, Cancer associated surface antigen, Cancer associated surface antigen RCAS1, Cancer-associated surface antigen RCAS1, EB9, EBAG 9, EBAG9, Estrogen receptor binding fragment associated gene 9 protein, Estrogen receptor binding site associated antigen 9, estrogen receptor binding site associated, antigen, 9, Estrogen receptor-binding fragment-associated gene 9 protein, PDAF, RCAS 1, RCAS1_HUMAN, Receptor binding cancer antigen expressed on SiSo cells, Receptor-binding cancer antigen expressed on SiSo cells
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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