Neurotrophin 3 ist ein Gen, das durch das Symbol NTF3 kodiert wird. Im Allgemeinen auch bezeichnet als: Neurotrophin-3; NT-3; HDNF; Nerve growth factor 2; NGF-2; Neurotrophic factor; NTF3. Neurotrophin 3 hat eine Masse von 29.36kDa und eine Aminosäurelänge von 257.
Wir bieten 2 Neurotrophin 3proteine an
Gen- und Proteininformationen
UniProt Zusammenfassung
Seems to promote the survival of visceral and proprioceptive sensory neurons.
Entrez Zusammenfassung
The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse.
Gewebespezifität
Brain and peripheral tissues.
Sequenzähnlichkeiten
Belongs to the NGF-beta family.