Neuritin ist ein Gen, das durch das Symbol NRN1 kodiert wird. Im Allgemeinen auch bezeichnet als: NRN1; NRN. Neuritin hat eine Masse von 15.33kDa und eine Aminosäurelänge von 142.
Wir bieten 2 Neuritinproteine an
Gen- und Proteininformationen
UniProt Zusammenfassung
Promotes neurite outgrowth and especially branching of neuritic processes in primary hippocampal and cortical cells.
Entrez Zusammenfassung
This gene encodes a member of the neuritin family, and is expressed in postmitotic-differentiating neurons of the developmental nervous system and neuronal structures associated with plasticity in the adult. The expression of this gene can be induced by neural activity and neurotrophins. The encoded protein contains a consensus cleavage signal found in glycosylphoshatidylinositol (GPI)-anchored proteins. The encoded protein promotes neurite outgrowth and arborization, suggesting its role in promoting neuritogenesis. Overexpression of the encoded protein may be associated with astrocytoma progression. Alternative splicing results in multiple transcript variants.
Sequenzähnlichkeiten
Belongs to the neuritin family.
Zellort
Cell membrane. Cell junction > Synapse.
