LFA3 ist ein Gen, das durch das Symbol CD58 kodiert wird. Im Allgemeinen auch bezeichnet als: Lymphocyte function-associated antigen 3; Ag3; Surface glycoprotein LFA-3; CD58. LFA3 hat eine Masse von 28.15kDa und eine Aminosäurelänge von 250.
Wir bieten 3 LFA3proteine an
Gen- und Proteininformationen
UniProt Zusammenfassung
Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.
Entrez Zusammenfassung
This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. The protein is localized to the plasma membrane. Alternatively spliced transcript variants have been described.
