Epigen ist ein Gen, das durch das Symbol EPGN kodiert wird. Andere Namen sind: Epithelial mitogen; EPG; EPGN. Epigen hat eine Masse von 17.09kDa und eine Aminosäurelänge von 154.
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Gen- und Proteininformationen
UniProt Zusammenfassung
Promotes the growth of epithelial cells. May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases.
Entrez Zusammenfassung
The protein encoded by this gene is a member of the epidermal growth factor family. Members of this family are ligands for the epidermal growth factor receptor and play a role in cell survival, proliferation and migration. This protein has been reported to have high mitogenic activity but low affinity for its receptor. Expression of this transcript and protein have been reported in cancer specimens of the breast, bladder, and prostate. Alternative splicing results in multiple transcript variants.
