CD80 ist ein Gen, das durch das Symbol CD80 kodiert wird. Andere Namen sind: T-lymphocyte activation antigen Activation B7-1 antigen; BB1; CTLA-4 counter-receptor B7.1; B7; CD28LG; CD28LG1; LAB7. CD80 hat eine Masse von 33.05kDa und eine Aminosäurelänge von 288.
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Gen- und Proteininformationen
UniProt Zusammenfassung
Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation.
Entrez Zusammenfassung
The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy.
Gewebespezifität
Expressed on activated B-cells, macrophages and dendritic cells.
