CD34 ist ein Gen, das durch das Symbol CD34 kodiert wird. Es ist auch bekannt als Hematopoietic progenitor cell antigen CD34. CD34 hat eine Masse von 40.72kDa und eine Aminosäurelänge von 385.
Wir bieten 5 CD34proteine an
Gen- und Proteininformationen
UniProt Zusammenfassung
Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.
Entrez Zusammenfassung
The protein encoded by this gene may play a role in the attachment of stem cells to the bone marrow extracellular matrix or to stromal cells. This single-pass membrane protein is highly glycosylated and phosphorylated by protein kinase C. Two transcript variants encoding different isoforms have been found for this gene.
Gewebespezifität
Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues.
Sequenzähnlichkeiten
Belongs to the CD34 family.
Posttranslationale Modifikation
Highly glycosylated.
