CCL27 ist ein Gen, das durch das Symbol CCL27 kodiert wird. Andere Namen sind: C-C motif chemokine 27; CC chemokine ILC; Cutaneous T-cell-attracting chemokine; CTACK; ESkine; IL-11 R-alpha-locus chemokine; Skinkine; Small-inducible cytokine A27; ILC; SCYA27. CCL27 hat eine Masse von 12.62kDa und eine Aminosäurelänge von 112.
Wir bieten 3 CCL27proteine an
Gen- und Proteininformationen
UniProt Zusammenfassung
Chemotactic factor that attracts skin-associated memory T-lymphocytes. May play a role in mediating homing of lymphocytes to cutaneous sites. Binds to CCR10.
Entrez Zusammenfassung
This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation.
Gewebespezifität
Testis, thymus, placenta, ovary and skin.
Sequenzähnlichkeiten
Belongs to the intercrine beta (chemokine CC) family.
