Apolipoprotein D ist ein Gen, das durch das Symbol APOD kodiert wird. Andere Namen sind: Apo-D; APOD. Apolipoprotein D hat eine Masse von 21.28kDa und eine Aminosäurelänge von 189.
Wir bieten 3 Apolipoprotein Dproteine an
Gen- und Proteininformationen
UniProt Zusammenfassung
APOD occurs in the macromolecular complex with lecithin-cholesterol acyltransferase. It is probably involved in the transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts.
Entrez Zusammenfassung
This gene encodes a component of high density lipoprotein that has no marked similarity to other apolipoprotein sequences. It has a high degree of homology to plasma retinol-binding protein and other members of the alpha 2 microglobulin protein superfamily of carrier proteins, also known as lipocalins. This glycoprotein is closely associated with the enzyme lecithin:cholesterol acyltransferase - an enzyme involved in lipoprotein metabolism.
Gewebespezifität
Expressed in liver, intestine, pancreas, kidney, placenta, adrenal, spleen, fetal brain tissue and tears.
Sequenzähnlichkeiten
Belongs to the calycin superfamily. Lipocalin family.
Posttranslationale Modifikation
N-glycosylatd. N-glycan heterogeneity at Asn-65: Hex5HexNAc4 (major) and Hex6HexNAc5 (minor); at Asn-98: Hex5HexNAc4 (minor), dHex1Hex5HexNAc4 (major), dHex1Hex6HexNAc5 (minor) and dHex1Hex7HexNAc6 (minor).