Es ist auch bekannt als Genome polyprotein. Zika Virus NS1 hat eine Masse von 378.74kDa und eine Aminosäurelänge von 3419.
Wir bieten 4 antikörper gegen Zika Virus NS1, aufgewachsen in Kaninchen, welche geeignet sind für WB, ELISA and IP.
Gen- und Proteininformationen
UniProt Zusammenfassung
Plays a role in virus budding by binding to the cell membrane and gathering the viral RNA into a nucleocapsid that forms the core of the mature virus particle. During virus entry, may induce genome penetration into the host cytoplasm after hemifusion induced by the surface proteins. Can migrate to the cell nucleus where it modulates host functions.
Sequenzähnlichkeiten
In the N-terminal section; belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0-1 NS5-type methyltransferase family.
Posttranslationale Modifikation
Specific enzymatic cleavages in vivo yield mature proteins. Cleavages in the lumen of endoplasmic reticulum are performed by host signal peptidase, whereas cleavages in the cytoplasmic side are performed by serine protease NS3. Signal cleavage at the 2K-4B site requires a prior NS3 protease-mediated cleavage at the 4A-2K site.
Zellort
Virion. Host nucleus. Host cytoplasm. Host cytoplasm > Host perinuclear region.
