ZDHHC9 ist ein Gen, das durch das Symbol ZDHHC9 kodiert wird. Es ist auch bekannt als: Palmitoyltransferase Zinc finger DHHC domain-containing protein 9; DHHC-9; Zinc finger protein 379; Zinc finger protein 380; CXorf11; ZDHHC10; ZNF379; ZNF380. ZDHHC9 hat eine Masse von 40.92kDa, eine Aminosäurelänge von 364, und ist an Mental retardation, X-linked, syndromic, ZDHHC9-related beteiligt.
Wir bieten 8 antikörper gegen ZDHHC9, aufgewachsen in Kaninchen, welche geeignet sind für WB, IHC, ELISA and IP mit Proben abgeleitet von Human, Maus und Ratte.
Gen- und Proteininformationen
UniProt Zusammenfassung
The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS.
Entrez Zusammenfassung
This gene encodes an integral membrane protein that is a member of the zinc finger DHHC domain-containing protein family. The encoded protein forms a complex with golgin subfamily A member 7 and functions as a palmitoyltransferase. This protein specifically palmitoylates HRAS and NRAS. Mutations in this gene are associated with X-linked cognitive disability. Alternate splicing results in multiple transcript variants that encode the same protein.
Gewebespezifität
Highly expressed in kidney, skeletal muscle, brain, lung and liver. Absent in thymus, spleen and leukocytes.
Rolle bei Krankheiten
Mental retardation, X-linked, syndromic, ZDHHC9-related: A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. Some MRXSZ patients have marfanoid habitus as an additional feature.
Sequenzähnlichkeiten
Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
Zellort
Endoplasmic reticulum membrane. Golgi apparatus membrane.
