Vitronectin ist ein Gen, das durch das Symbol VTN kodiert wird. Es ist auch bekannt als: VN; S-protein; Serum-spreading factor; V75; VTN. Vitronectin hat eine Masse von 54.31kDa und eine Aminosäurelänge von 478.
Wir bieten 7 antikörper gegen Vitronectin, aufgewachsen in Kaninchen und Maus, welche geeignet sind für WB, IHC, ELISA and ICC/IF mit Proben abgeleitet von Human, Maus und Ratte.
Gen- und Proteininformationen
UniProt Zusammenfassung
Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway.
Entrez Zusammenfassung
The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.
Gewebespezifität
Expressed in the retina pigment epithelium (at protein level) (PubMed:25136834). Plasma.
Posttranslationale Modifikation
Sulfated on tyrosine residues.
Zellort
Secreted > Extracellular space.
