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Anti-Tollip Antikörper

9 Products

Tollip ist ein Gen, das durch das Symbol TOLLIP kodiert wird. Es ist auch bekannt als Toll-interacting protein. Tollip hat eine Masse von 30.28kDa und eine Aminosäurelänge von 274.

Wir bieten 9 antikörper gegen Tollip, aufgewachsen in Kaninchen, Maus und Ratte, welche geeignet sind für WB, IHC, ELISA, ICC/IF and IP mit Proben abgeleitet von Human, Maus und Ratte.

Gen- und Proteininformationen

UniProt Zusammenfassung
Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity (PubMed:11751856). Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (PubMed:25042851).
Entrez Zusammenfassung
This gene encodes a ubiquitin-binding protein that interacts with several Toll-like receptor (TLR) signaling cascade components. The encoded protein regulates inflammatory signaling and is involved in interleukin-1 receptor trafficking and in the turnover of IL1R-associated kinase. Several transcript variants encoding different isoforms have been found for this gene.
Sequenzähnlichkeiten
Belongs to the tollip family.
Posttranslationale Modifikation
Phosphorylated by IRAK1 upon stimulation by IL-1 or microbial products.
Zellort
Cytoplasm.
Western Blot - Anti-Tollip Antibody (A13955) - Antibodies.com
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Western Blot - Anti-Tollip Antibody (A307074) - Antibodies.com
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Anti-Tollip Antibody from Bioworld Technology (BS6938) - Antibodies.com
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Western blot - TOLLIP Antibody from Signalway Antibody (32664) - Antibodies.com
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Western blot - TOLLIP Antibody from Signalway Antibody (24389) - Antibodies.com
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Western blot - TOLLIP Antibody from Signalway Antibody (24388) - Antibodies.com
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Western blot - TOLLIP Antibody from Signalway Antibody (35328) - Antibodies.com

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