TIM 1 ist ein Gen, das durch das Symbol HAVCR1 kodiert wird. Es ist auch bekannt als: Hepatitis A virus cellular receptor 1; HAVcr-1; Kidney injury molecule 1; KIM-1; T-cell immunoglobulin and mucin domain-containing protein 1; TIMD-1; T-cell immunoglobulin mucin receptor 1; TIM; T-cell membrane protein 1; HAVCR1; KIM1; TIM1; TIMD1. TIM 1 hat eine Masse von 39.25kDa und eine Aminosäurelänge von 364.
Wir bieten 10 antikörper gegen TIM 1, aufgewachsen in Kaninchen, Ziege und Ratte, welche geeignet sind für WB, IHC, ELISA, ICC/IF and FC mit Proben abgeleitet von Human, Maus und Ratte.
Gen- und Proteininformationen
UniProt Zusammenfassung
May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4 (By similarity). May play a role in kidney injury and repair.
Entrez Zusammenfassung
The protein encoded by this gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4, 12 and 19.
Gewebespezifität
Widely expressed, with highest levels in kidney and testis. Expressed by activated CD4+ T-cells during the development of helper T-cells responses.
Sequenzähnlichkeiten
Belongs to the immunoglobulin superfamily. TIM family.
