SPACA3 ist ein Gen, das durch das Symbol SPACA3 kodiert wird. Es ist auch bekannt als: Sperm acrosome membrane-associated protein 3; Cancer/testis antigen 54; CT54; Lysozyme-like acrosomal sperm-specific secretory protein ALLP-17; Lysozyme-like protein 3; Sperm lysozyme-like protein 1; Sperm protein reactive with antisperm antibodies; Sperm protein reactive with ASA; LYC3; LYZL3; SLLP1; SPRASA. SPACA3 hat eine Masse von 23.43kDa und eine Aminosäurelänge von 215.
Wir bieten 14 antikörper gegen SPACA3, aufgewachsen in Kaninchen, welche geeignet sind für WB, IHC, ELISA and IP mit Proben abgeleitet von Human, Maus und Ratte.
Gen- und Proteininformationen
UniProt Zusammenfassung
Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro.
Entrez Zusammenfassung
The protein encoded by this gene is a sperm surface protein that may be involved in adhesion to the egg prior to fertilization. While the encoded protein has significant similarity to lysozyme at the amino acid level, it has no detectable bacteriocidal activity. Several transcript variants encoding different isoforms have been found for this gene.
Gewebespezifität
The processed form is expressed in sperm (at protein level). Expressed in testis, epididymis and placenta.
Sequenzähnlichkeiten
Belongs to the glycosyl hydrolase 22 family.
Posttranslationale Modifikation
The processed form derives from the membrane form by proteolytic processing.
Zellort
Cytoplasmic vesicle > Secretory vesicle > Acrosome membrane.
Anterior acrosome in non-capacitated spermatozoa and retained in the equatorial segment and in the luminal face of both the inner and outer acrosomal membranes following capacitation and the acrosome reaction.
