SNX4 ist ein Gen, das durch das Symbol SNX4 kodiert wird. Es ist auch bekannt als Sorting nexin-4. SNX4 hat eine Masse von 51.91kDa und eine Aminosäurelänge von 450.
Wir bieten 7 antikörper gegen SNX4, aufgewachsen in Kaninchen und Ziege, welche geeignet sind für WB, IHC and ELISA mit Proben abgeleitet von Human, Maus und Ratte.
Gen- und Proteininformationen
UniProt Zusammenfassung
Involved in the regulation of endocytosis and in several stages of intracellular trafficking (PubMed:12668730). Plays a role in recycling endocytosed transferrin receptor and prevent its degradation.
Entrez Zusammenfassung
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associated with the long isoform of the leptin receptor and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor in cell cultures, but its function is unknown. This protein may form oligomeric complexes with family members. Two transcript variants, one protein coding and the other non-protein coding, have been found for this gene.
Sequenzähnlichkeiten
Belongs to the sorting nexin family.
Zellort
Early endosome. Early endosome membrane.
Also detected on a juxtanuclear endocytic recycling compartment (ERC).
