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Anti-SERCA1 ATPase Antikörper

6 Products

SERCA1 ATPase ist ein Gen, das durch das Symbol ATP2A1 kodiert wird. Es ist auch bekannt als: Sarcoplasmic/endoplasmic reticulum calcium ATPase 1; SERCA1; Calcium pump 1; Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform; Endoplasmic reticulum class 1/2 Ca(2+) ATPase; ATP2A1. SERCA1 ATPase hat eine Masse von 110.25kDa, eine Aminosäurelänge von 1001, und ist an Brody myopathy beteiligt.

Wir bieten 6 antikörper gegen SERCA1 ATPase, aufgewachsen in Kaninchen, welche geeignet sind für WB, IHC, ELISA and ICC/IF mit Proben abgeleitet von Human, Maus und Ratte.

Gen- und Proteininformationen

UniProt Zusammenfassung
Key regulator of striated muscle performance by acting as the major Ca(2+) ATPase responsible for the reuptake of cytosolic Ca(2+) into the sarcoplasmic reticulum. Catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen (By similarity). Contributes to calcium sequestration involved in muscular excitation/contraction (PubMed:10914677).
Entrez Zusammenfassung
This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in three transcript variants encoding different isoforms.
Gewebespezifität
Skeletal muscle, fast twitch muscle (type II) fibers.
Rolle bei Krankheiten
Brody myopathy: A disorder of muscle function that is characterized by painless muscle cramping and exercise-induced impairment of muscle relaxation.
Sequenzähnlichkeiten
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
Zellort
Endoplasmic reticulum membrane. Sarcoplasmic reticulum membrane.
Western Blot - Anti-SERCA1 ATPase Antibody [ARC2207] (A305365) - Antibodies.com
(3)
Western Blot - Anti-ATP2A1 Antibody (C18472) - Antibodies.com
(2)
Produkt anzeigen10µg Versuchsgrößen
Western Blot - Anti-SERCA1 ATPase Antibody (A8528) - Antibodies.com
Western blot - SERCA1 Polyclonal Antibody from Signalway Antibody (41428) - Antibodies.com
ATP2A1 Antibody from Signalway Antibody (37728) - Antibodies.com
(2)
Anti-SERCA1 (D580) Antibody from Bioworld Technology (BS3934) - Antibodies.com

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