SCP2 ist ein Gen, das durch das Symbol SYCP2 kodiert wird. Es ist auch bekannt als: Synaptonemal complex protein 2; SCP-2; Synaptonemal complex lateral element protein; hsSYCP2. SCP2 hat eine Masse von 175.64kDa und eine Aminosäurelänge von 1530.
Wir bieten 5 antikörper gegen SCP2, aufgewachsen in Kaninchen, welche geeignet sind für WB, IHC and ICC/IF mit Proben abgeleitet von Human, Maus und Ratte.
Gen- und Proteininformationen
UniProt Zusammenfassung
Major component of the axial/lateral elements of synaptonemal complexes (SCS) during meiotic prophase. Plays a role in the assembly of synaptonemal complexes. Required for normal meiotic chromosome synapsis during oocyte and spermatocyte development and for normal male and female fertility. Required for insertion of SYCP3 into synaptonemal complexes. May be involved in the organization of chromatin by temporarily binding to DNA scaffold attachment regions. Requires SYCP3, but not SYCP1, in order to be incorporated into the axial/lateral elements.
Entrez Zusammenfassung
The synaptonemal complex is a proteinaceous structure that links homologous chromosomes during the prophase of meiosis. The protein encoded by this gene is a major component of the synaptonemal complex and may bind DNA at scaffold attachment regions. The encoded protein requires synaptonemal complex protein 3, but not 1, for inclusion in the synaptonemal complex.
Sequenzähnlichkeiten
Belongs to the SYCP2 family.
Posttranslationale Modifikation
Phosphorylated.
Zellort
Nucleus. Chromosome.
In axial/lateral elements of the tripartite segments of synaptonemal complexes.
